日本骨骼肌细胞使实验鼠恢复了正常分泌抗肌萎缩蛋白
新华网东京1月24日电(记者钱铮)日本科学家对基因异常实验鼠进行的研究表明,用女性子宫内膜细胞培养出的肌细胞也许能用于治疗肌营养不良症。肌营养不良症是由遗传因素所导致的原发性骨骼肌坏死性疾病,症状为患者肌细胞逐渐坏死并被脂肪细胞所取代,结果导致肌肉功能丧失,严重时呼吸和心脏机能会受到影响甚至致人死亡。患者基因异常致使肌细胞膜含有的抗肌萎缩蛋白不能正常分泌,通常被认为是肌营养不良症的病因。
据《日经产业新闻》24日报道,日本国立儿童健康和发展研究所梅泽明弘等人在研究中首先对女性志愿者提供的经血进行培养,使其中一些具有分化能力的子宫内膜间质细胞成长为骨骼肌细胞。他们将这些细胞注入先天缺失抗肌萎缩蛋白的实验鼠体内后发现,注入的骨骼肌细胞与体内原有的骨骼肌细胞融合,最终使实验鼠恢复了正常分泌抗肌萎缩蛋白的功能。2007年01月24日 18:42:33 来源:新华网
原文地址http://news.xinhuanet.com/world/2007-01/24/content_5648286.htm
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